Penicillins for MSSA has pneumonia . A sputum culture grows methicillin-susceptible S. aureus susceptible to oxacillin, amoxicillin-clavulanate, and cefazolin. Oral amoxicillin is initially ordered. Is this appropriate? A. YesB. No How did others respond? Reveal the answer Best Answer No Explanation: MSSA commonly makes a penicillinase and should be considered resistant to penicillin, amoxicillin, and …
Ceftriaxone Guided IV to PO is admitted with pyelonephritis. Blood and urine cultures grow E. coli with the below susceptibilities. They have a QTc of 502 ms and a sulfa allergy. Amox – R Amox-clav – R Cefazolin – R Ceftriaxone – S Ciprofloxacin – S TMP-SMX – S Which of the following is best …
Cephalosporins for VGS is admitted with a dental abscess. Blood cultures grow Viridans Group Streptococcus (VGS) that is susceptible to penicillin. Is cephalexin and metronidazole a good oral stepdown option to complete therapy? YesNo How did others respond? Reveal the answer Best Answer No Explanation: Cephalexin has unreliable activity against VGS. Penicillin activity against VGS …
Cidal vs Static A is admitted to the ICU for community-acquired pneumonia . They have a history of MRSA and a vancomycin allergy. Should linezolid be avoided because it is bacteriostatic? A. YesB. No How did others respond? Reveal the answer Best Answer No Explanation: Bacteriostatic and bactericidal are not clinically relevant terms and …
De-escalation is For Everyone An ICU patient is on day 3 of empiric antibiotics for pneumonia. The patient is improving and cultures are negative. Which of the following is a benefit from antimicrobial de-escalation? A. Lower AKI riskB. Higher mortalityC. Cost increases How did others respond? Reveal the answer Best Answer Lower AKI risk Antimicrobial …
Duration of Therapy in Uncomplicated CoNS CLABSI An inpatient is diagnosed with a CoNS CRBSI. Her central line is removed, she is clinically stable, and repeat blood cultures are obtained. She has no implanted prosthetic material, but many antibiotic allergies. The team would like to monitor repeat blood cultures off antibiotics. Is this appropriate? How …
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Antibiotic Decision Making Moments Antibiotic decision making ends after a diagnosis is made, cultures are obtained, and empiric antibiotics are started. True or False? How did others respond? Reveal the answer Best Answer: False Explanation: There are four moments of antibiotic decision making. After the first two of 1) making a diagnosis and 2) obtaining …
Duration of Antibiotics in Non-Severe CAP A 41 year old with a past medical history of hypertension is on ampicillin-sulbactam and azithromycin for community-acquired pneumonia . On day 3, he is improved and ready for discharge. What total duration of antibiotics should be used? A. 3 daysB. 5 daysC. 7 days How did others respond? …
Duration of Therapy in Male UTI A man presents with dysuria without systemic signs of infection. He is diagnosed with an uncomplicated urinary tract infection and prescribed nitrofurantoin. Which duration of antibiotics is best? A. 3 daysB. 5 daysC. 10 days How did others respond? Reveal the answer Best Answer: 5 days Historically, some have …
Antibiotic De-escalation in Culture Negative Pneumonia is on cefepime, azithromycin, and vancomycin for community-acquired pneumonia . On day 3, 1500 mg azithromycin has been completed, the patient has improved , and a sputum culture shows normal respiratory flora. The antibiotics are deescalated to oral amoxicillin-clavulanate. Is this appropriate? How did others respond? Reveal the answer …
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