Healthcare-Associated CNS Infection

Healthcare-Associated CNS Infection is admitted with head trauma and prescribed broad spectrum antibiotics for a healthcare-associated CNS infection. Which anti-pseudomonal agent SHOULD NOT be used? A. CefepimeB. Piperacillin/tazobactamC. Meropenem How did others respond? Reveal the answer Best Answer: Piperacillin/tazobactam Explanation: Why not? Pharmacokinetics! Tazobactam DOES NOT cross the blood brain barrier well and therefore is …

Antibiotics in AECOPD

Antibiotics in AECOPD has baseline COPD and is admitted to the with dyspnea & sputum purulence but NO CHANGE in volume of sputum production. Should antibiotics be prescribed for an acute exacerbation of COPD? How did others respond? Reveal the answer Best Answer: Yes πŸ’Š Explanation: GOLD guidelines recommend antibiotics for AECOPD based on 3 …

Pre-operative Urine Screening

Pre-operative Urine Screening is scheduled for hip arthroplasty later this week. She presents today for pre-op screening in clinic and is feeling well. Should a urinalysis/urine culture be collected? How did others respond? Reveal the answer Best Answer: No πŸ‘Ž Explanation: IDSA guidelines recommend AGAINST screening and treatment for asymptomatic bacteriuria (ASB) in nonurologic surgery. …

Alcohol and Metronidazole

Alcohol and Metronidazole presents with trichomoniasis. She also reports drinking 2 glasses of wine most nights Your student asks if she should still be prescribed metronidazole given alcohol use. How did others respond? Reveal the answer Best Answer: Yes give metronidazole πŸ’Š Explanation: Labeling for metronidazole recommends avoiding alcohol within 72 hours of taking metronidazole …

Why Prolong a Beta-Lactam Infusion?

Why Prolong a Beta-Lactam Infusion? Prolonged infusions of beta-lactam antibiotics increase time above MIC. Which patient would MOST likely benefit from a prolonged infusion? 1. Poor renal function 2. Critically-ill + MIC 3. Clinically stable + low MIC How did others respond? Reveal the answer Best Answer: Patient 2 πŸ‘±πŸΌβ€β™€οΈ Explanation: Prolonged infusions of beta-lactams …

Bilateral Lower Extremity Cellulitis

Bilateral Lower Extremity Cellulitis A with CHF presents with shortness of breath & redness/swelling of both legs. He is afebrile & WBC is normal. Does he need antibiotics for bilateral lower extremity cellulitis? A. Yes IV antibiotics πŸ’‰B. Yes PO antibiotics πŸ’ŠC. No antibiotics 🚫 How did others respond? Reveal the answer Best Answer: No …

Beta-Lactam Selection in CAP

Beta-Lactam Selection in Community-Acquired Pneumonia A medical student is presenting on a patient with community-acquired pneumonia. The team agrees they want to treat with a beta-lactam + macrolide. Which beta-lactam recommended per the 2019 ATS/IDSA guidelines is LOWEST risk for Clostridioides difficile? A. Ampicillin/sulbactamB. CefotaximeC. CeftriaxoneD. Ceftaroline How did others respond? Reveal the answer Best …

Antibiotic Duration in Intra-Abdominal Infections

Antibiotic Duration in Intra-Abdominal Infections is admitted to the for cholecystitis & had a percutaneous drain placed yesterday. Her drain will be removed before discharge tomorrow. When should antibiotics be stopped? A. Post-op day 4B. Day 7C. Day 10D. Day 14 How did others respond? Reveal the answer Best Answer: Post-op Day 4 2024 Surgical …

Anaerobe Awareness in Intra-Abdominal Infections

Anaerobe Awareness in Intra-Abdominal Infections is admitted to the with perforated diverticulitis & a blood culture growing PAN-SUSCEPTIBLE E. coli What is the MOST appropriate antibiotic regimen? A. AmpicillinB. Ampicillin/sulbactamC. Ceftriaxone How did others respond? Reveal the answer Best Answer Ampicillin/sulbactam Explanation: Surgical Infection Society guidelines recommend anti-anaerobic activity in intra-abdominal infections, even when de-escalating. …