Author: Sarah Moore

Anti-Enterococcal Antibiotics in Intra-Abdominal Infections is receiving chemotherapy for colon cancer and admitted to the ICU with septic shock from an intra-abdominal infection. Should coverage for Enterococcus spp. be considered? How did others respond? Reveal the answer Best Answer: Yes, cover Enterococcus 🦠 Explanation: Enterococcus spp, which is part of normal GI flora, rarely cause …

Read more “Anti-Enterococcal Antibiotics in Intra-Abdominal Infections”

Staphylococcus lugdunensis is admitted to the and had a skin abscess requiring I&D. A blood culture grows Staphylococcus lugdunensis (a coagulase-negative species) Is this likely a contaminant? How did others respond? Reveal the answer Best Answer: No Explanation: Unlike other coagulase-negative Staphylococcus spp., S. lugdunensis is very virulent and associated with ⬆️ mortality. Like S. …

Read more “Staphylococcus lugdunensis”

Antibiotic Duration after Appendectomy presented to the with uncomplicated appendicitis. She had a laparoscopic appendectomy yesterday. When should antibiotics be stopped? A. 14 days totalB. 4 days post op C. 24-48 hours post op D. Now! How did others respond? Reveal the answer Best Answer: Now! 🛑 Explanation: 2017 Surgical Infection Society guidelines recommend stopping …

Read more “Antibiotic Duration after Appendectomy”

COVID-19 Management is admitted with COVID-19. His symptoms began 2 weeks ago. He is on high flow oxygen but NOT immunocompromised. What is the best treatment option? A. Baricitinib + steroidB. RemdesivirC. Remdesivir + steroidD. Azithromycin How did others respond? Reveal the answer Best Answer: Baricitinib + steroid Explanation: The archived NIH COVID-19 guidelines make …

Read more “COVID-19 Management”

Healthcare-Associated CNS Infection is admitted with head trauma and prescribed broad spectrum antibiotics for a healthcare-associated CNS infection. Which anti-pseudomonal agent SHOULD NOT be used? A. CefepimeB. Piperacillin/tazobactamC. Meropenem How did others respond? Reveal the answer Best Answer: Piperacillin/tazobactam Explanation: Why not? Pharmacokinetics! Tazobactam DOES NOT cross the blood brain barrier well and therefore is …

Read more “Healthcare-Associated CNS Infection”

Antibiotics in AECOPD has baseline COPD and is admitted to the with dyspnea & sputum purulence but NO CHANGE in volume of sputum production. Should antibiotics be prescribed for an acute exacerbation of COPD? How did others respond? Reveal the answer Best Answer: Yes 💊 Explanation: GOLD guidelines recommend antibiotics for AECOPD based on 3 …

Read more “Antibiotics in AECOPD”

Pre-operative Urine Screening is scheduled for hip arthroplasty later this week. She presents today for pre-op screening in clinic and is feeling well. Should a urinalysis/urine culture be collected? How did others respond? Reveal the answer Best Answer: No 👎 Explanation: IDSA guidelines recommend AGAINST screening and treatment for asymptomatic bacteriuria (ASB) in nonurologic surgery. …

Read more “Pre-operative Urine Screening”

Alcohol and Metronidazole presents with trichomoniasis. She also reports drinking 2 glasses of wine most nights Your student asks if she should still be prescribed metronidazole given alcohol use. How did others respond? Reveal the answer Best Answer: Yes give metronidazole 💊 Explanation: Labeling for metronidazole recommends avoiding alcohol within 72 hours of taking metronidazole …

Read more “Alcohol and Metronidazole”

Why Prolong a Beta-Lactam Infusion? Prolonged infusions of beta-lactam antibiotics increase time above MIC. Which patient would MOST likely benefit from a prolonged infusion? 1. Poor renal function 2. Critically-ill + MIC 3. Clinically stable + low MIC How did others respond? Reveal the answer Best Answer: Patient 2 👱🏼‍♀️ Explanation: Prolonged infusions of beta-lactams …

Read more “Why Prolong a Beta-Lactam Infusion?”