Clostridioides difficile Prophylaxis A 70 year old with leukemia is admitted to the for febrile neutropenia. She was treated for C. difficile colitis last month. She is started on cefepime. She is not currently having diarrhea. Which is the BEST option? A. Test for C. difficileB. Start fidaxomicinC. Start oral vancomycin prophylaxis How did others respond? …
Empiric Pip-Tazo in Intra-Abdominal Infections 2 patients are admitted & started on empiric piperacillin/tazobactam. Patient 1: with community-onset appendicitis Patient 2: with pancreatic cancer s/p recent Whipple with anastomotic leak & peritonitis In which patient is it REASONABLE to narrow antibiotics? How did others respond? Reveal the answer Best Answer: Patient 1 👨🏾 Explanation: 2017 …
The Clinically Non-Responding Patient has a history of heart failure and is admitted for respiratory distress. He is diagnosed with pneumonia After 2 days, his oxygen requirements are but he is afebrile. Which is the MOST APPROPRIATE next action? How did others respond? Reveal the answer Best Answer: Evaluate fluid status Explanation: 👴🏼 has a …
MRSA Nasal Screening After Vancomycin has pneumonia and is on day 5 of vancomycin. He has a history of MRSA No respiratory cultures have been collected. Should a MRSA swab be collected now? How did others respond? Reveal the answer Best Answer: No Explanation: The utility of MRSA 👃 swabs after anti-MRSA therapy is questionable …
Carbapenem-Resistant Acinetobacter baumannii is in the for pneumonia from carbapenem-resistant Acinetobacter baumannii (CRAB). She is started on minocycline. The team wants to use combination therapy Which is NOT an appropriate second agent? How did others respond? Reveal the answer Best Answer: Tigecycline Explanation: Sulbactam-containing antibiotics are the cornerstone of treating CRAB infections & should …
MRSA Nasal Screening in Diabetic Foot Infection is started on empiric vancomycin for a diabetic foot infection (DFI). His MRSA nasal screening is & he has NO history of MRSA Can vancomycin be STOPPED? How did others respond? Reveal the answer Best Answer: Yes, stop 🛑 Explanation: A small study in patients with DFIs and …
Antibiotic Lock Therapy has a S. epidermidis port infection and is receiving systemic and lock vancomycin. Your student asks when changing the locksolution if it should be pushed through the line to ensure the patient gets the full dose. You tell them… How did others respond? Reveal the answer Best Answer: No Explanation: Best practice …
Duration of Therapy in AECOPD has COPD with sputum production & purulence. He is prescribed doxycycline for an acute exacerbation of COPD (AECOPD). What is the MOST APPROPRIATE duration of therapy? How did others respond? Reveal the answer Best Answer: 5 days Explanation: 2024 GOLD guidelines recommend 5-7 days of antibiotics for AECOPD. A 2022 …
Vaccines in Asplenia was in a car accident which lacerated his spleen. He was admitted to trauma and underwent an emergent splenectomy. Which bacteria should he be vaccinated for post-splenectomy? How did others respond? Reveal the answer Best Answer: All of the above 🦠🦠🦠 Explanation: Patients with functional or anatomical asplenia should be vaccinated for …
Catheter Salvage has AML and a port in place for chemotherapy. Her blood culture is growing S. epidermidis. The team does NOT plan to remove her port. What is the BEST antibiotic plan? How did others respond? Reveal the answer Best Answer Vancomycin IV + lock Explanation: In catheter-related bloodstream infections (CRBSI) where catheter removal …