Why Prolong a Beta-Lactam Infusion?

Prolonged infusions of beta-lactam antibiotics increase time above MIC.

Which patient would MOST likely benefit from a prolonged infusion?

1. Poor renal function
2. Critically-ill + MIC
3. Clinically stable + low MIC

How did others respond?

Reveal the answer

Best Answer:

Patient 2 👱🏼‍♀️

Explanation: Prolonged infusions of beta-lactams can be utilized in any scenario to optimize time>MIC but are most likely to improve clinical outcomes in:
-confirmed infection
-increased renal clearance
-critical illness
-elevated MICs

An international consensus guideline recommends prolonging beta-lactam infusions in critically-ill adult patients 👨🏻‍🦳👱🏼‍♀️👨🏾‍🦲