Duplicate Anaerobic Activity A is admitted to the with a new intra-abdominal fluid collection after a recent partial colectomy. Which empiric treatment needs the ADDITION of metronidazole for anaerobic coverage? A. CefepimeB. MeropenemC. Piperacillin/tazobactam How did others respond? Reveal the answer Best Answer Cefepime Explanation: IDSA cIAI guideline states cefepime is the only option here …
Treatment of CRE A is seen in clinic with recurrent pyelonephritis. Her urine culture grows K. pneumoniae with this susceptibility: Meropenem = RTMP/SMX = SPIP/TAZ = I What is the BEST antibiotic choice based on available data? A. TMP/SMXB. CiprofloxacinC. Ceftazidime/AvibactamD. Cefiderocol How did others respond? Reveal the answer Best Answer TMP/SMX Explanation: Based on …
Itraconazole Absorption A is taking conventional itraconazole capsules for the treatment of pulmonary histoplasmosis infection Which administration method will itraconazole capsule absorption? A. Take with food B. Take without food C. Acid suppression drugs How did others respond? Reveal the answer Best Answer Take with food 🍔 Explanation:Itraconazole capsule 💊 absorption ⬆️ when the stomach …
Empiric Anti-pseudomonal Activity in DFI 3 patients present with diabetic foot infections: 1. with osteomyelitis & recent culture growing MSSA 2. with blisters from new shoes 3. with recent culture growing P. aeruginosa Who should receive EMPIRIC anti-pseudomonal coverage? How did others respond? Reveal the answer Best Answer Patient 3 🧔🏻♂️ given recent growth of …
Timing of Antibiotics in Diabetic Foot Infections A is admitted to the for a diabetic foot infection (DFI)with concern for osteomyelitis. He is not septic and awaiting surgical plans What is the BEST antibiotic plan? A. HOLD antibiotics B. Start vancomycinC. Start cefepimeD. Start vanc + cefepime How did others respond? Reveal the answer Best …
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Spontaneous Bacterial Peritonitis Prophylaxis A 48 year old is admitted to the with hematemesisHe has a history of alcohol use disorder and cirrhosis but no other health issues. Is spontaneous bacterial peritonitis (SBP) prophylaxis indicated? A. YesB. No How did others respond? Reveal the answer Best Answer Yes, SBP prophylaxis is indicated. Explanation: Primary SBP …
QTc Prolonging Antibiotics A 77 year old is admitted with an acute exacerbation of COPD A recent EKG shows her baseline QTc interval is 504 ms. Which antibiotic will NOT further prolong her QTc? A. MoxifloxacinB. DoxycyclineC. Azithromycin How did others respond? Reveal the answer Best Answer Doxycycline Explanation: Fluoroquinolone and macrolide antibiotics both can …
Cephalexin Dosing in Cystitis A with dysuria but no fever or flank pain is prescribed cephalexin 500 mg 2x daily. Drug references suggest up to 4x daily dosing. Should the frequency be changed? Yes, increase frequencyNo, keep frequency How did others respond? Reveal the answer Best Answer No, keep frequency Explanation: Pharmacokinetic data shows that …
Three versus Five Days of Azithromycin A is admitted with CAP. She is started on ceftriaxone and azithromycin 500 mg PO every 24 hours x days. A colleague asks why not use “Z-pak” dosing (500 mg x 1 then 250 mg every 24 hours x days total) What do you tell them? A. Dosing is …
Discordant Results : Amoxicillin-Clavulanate and Ampicillin-Sulbactam A with a drained intra-abdominal abscess was sent with amoxicillin/clavulanate An operative culture grows E. coli with this susceptibility: Ampicillin = RAmoxicillin/clavulanate = SAmpicillin/sulbactam = R Should antibiotics be changed? How did others respond? Reveal the answer Best Answer No, therapy is active ✅ Explanation: Discordant susceptibility between …
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