PEN-FASTby Sarah Moorein Patient Caseson Posted on PEN-FAST reports a penicillin allergy. You learn he had a non-itching rash in his early 20s but no difficulty breathing or need for treatment. Is it appropriate to challenge his penicillin allergy with oral amoxicillin? How did others respond? Reveal the answer Best Answer: Yes challenge π Explanation: This patient is at very low risk of a true penicillin allergy according to the PEN-FAST score. A randomized controlled trial found that PEN-FAST scores < 3 were noninferior to penicillin skin testing to assess oral challenge safety. πPull out PEN-FAST to determine if a penicillin allergy challenge and de-labeling is appropriate! π Learn how to calculate a PEN-FAST score by clicking on the link below. Click here for details/references