Linezolid or Vancomycin for MRSA Pneumonia

Linezolid or Vancomycin for MRSA Pneumonia A was recently in the for influenza.   He is readmitted 2 weeks later with pneumonia. Which EMPIRIC anti-MRSA agent is the best choice?1. Vancomycin2. Linezolid How did others respond? Reveal the answer Best Answer Vancomycin Explanation: Using empiric vancomycin can help preserve linezolid activity against vancomycin-resistant Enterococcus. Positioning …

Procalcitonin in Pneumonia

Procalcitonin in Pneumonia 3 patients with pneumonia on day 5 of antibiotics have a procalcitonin level drawn. PCT = 0.6 mcg/mL PCT = 0.1 mcg/mL PCT = 3.6 mcg/mL (was initially 7.2 mcg/mL) Who can most likely STOP antibiotics based on procalcitonin? How did others respond? Reveal the answer Best Answer Patient 2 👩🏻‍🦰 Explanation: …

Cefazolin vs Antistaphylococcal Penicillins

Cefazolin vs Antistaphylococcal Penicillins In which of the following patients would cefazolin be ADVANTAGEOUS over nafcillin for treatment of a MSSA infection? Patient 1 with CNS infection & recent C. difficile Patient 2 with osteomyelitis & hyperkalemia & LFTs How did others respond? Reveal the answer Best Answer Patient 2 🧔🏼 Explanation: Cefazolin is favorable …

Risk of C. difficile

Risk of C. difficile 3 patients are being discharged amoxicillin x 5 days cefdinir x 3 days levofloxacin x 10 days Whose antibiotic regimen is HIGHEST risk for C. difficile? How did others respond? Reveal the answer Best Answer 3️⃣ 👩🏻‍🦰 levofloxacin x 10 days Explanation: ALL antibiotics ⬆️ risk of C. difficile infection but …

Duplicate Anaerobic Activity

Duplicate Anaerobic Activity A is admitted to the with a new intra-abdominal fluid collection after a recent partial colectomy. Which empiric treatment needs the ADDITION of metronidazole for anaerobic coverage? A. CefepimeB. MeropenemC. Piperacillin/tazobactam How did others respond? Reveal the answer Best Answer Cefepime Explanation: IDSA cIAI guideline states cefepime is the only option here …

Treatment of CRE

Treatment of CRE A is seen in clinic with recurrent pyelonephritis. Her urine culture grows K. pneumoniae with this susceptibility: Meropenem = RTMP/SMX = SPIP/TAZ = I What is the BEST antibiotic choice based on available data? A. TMP/SMXB. CiprofloxacinC. Ceftazidime/AvibactamD. Cefiderocol How did others respond? Reveal the answer Best Answer TMP/SMX Explanation: Based on …

Itraconazole Absorption

Itraconazole Absorption A is taking conventional itraconazole capsules for the treatment of pulmonary histoplasmosis infection Which administration method will itraconazole capsule absorption? A. Take with food B. Take without food C. Acid suppression drugs How did others respond? Reveal the answer Best Answer Take with food 🍔 Explanation:Itraconazole capsule 💊 absorption ⬆️ when the stomach …

Empiric Pseudomonas aeruginosa Activity in DFI

Empiric Anti-pseudomonal Activity in DFI 3 patients present with diabetic foot infections: 1. with osteomyelitis & recent culture growing MSSA 2. with blisters from new shoes 3. with recent culture growing P. aeruginosa Who should receive EMPIRIC anti-pseudomonal coverage? How did others respond? Reveal the answer Best Answer Patient 3 🧔🏻‍♂️ given recent growth of …

Timing of Antibiotics in Diabetic Foot Infections

Timing of Antibiotics in Diabetic Foot Infections A is admitted to the for a diabetic foot infection (DFI)with concern for osteomyelitis. He is not septic and awaiting surgical plans What is the BEST antibiotic plan? A. HOLD antibiotics B. Start vancomycinC. Start cefepimeD. Start vanc + cefepime How did others respond? Reveal the answer Best …