Streptococcus anginosus Group

Streptococcus anginosus Group A patient with Streptococcus anginosus bacteremia is discovered to have an abscess. Which of the following is the best empiric treatment option? A. Ampicillin/sulbactamB. CeftriaxoneC. Levofloxacin + flagyl How did others respond? Reveal the answer Best Answer 💉Ampicillin/sulbactam Streptococcus anginosus group (SAG) organisms are highly susceptible to penicillins, and the ➕ of …

Anti-pseudomonals

Anti-pseudomonals A patient with osteomyelitis due to P. aeruginosa is going home with antibiotic therapy. Which antibiotic is NOT an option? Ertapenem Cefepime Ciprofloxacin How did others respond? Reveal the answer Best Answer Ertapenem Explanation: Ertapenem is not active 🛑 against Pseudomonas aeruginosa. Cefepime and ciprofloxacin are both options but remember quinolones are the ONLY …

Procalcitonin in AECOPD

Procalcitonin in AECOPD A patient presents to the hospital in an AECOPD. They have severe dyspnea, increased sputum volume, and purulence. Their procalcitonin is 0.06 ng/mL. Should this patient be started on antibiotics ? How did others respond? Reveal the answer Best Answer ✅ Yes Explanation: The GOLD guidelines recommend patients with the cardinal symptoms …

Linezolid or Vancomycin for MRSA Pneumonia

Linezolid or Vancomycin for MRSA Pneumonia A was recently in the for influenza.   He is readmitted 2 weeks later with pneumonia. Which EMPIRIC anti-MRSA agent is the best choice?1. Vancomycin2. Linezolid How did others respond? Reveal the answer Best Answer Vancomycin Explanation: Using empiric vancomycin can help preserve linezolid activity against vancomycin-resistant Enterococcus. Positioning …

Procalcitonin in Pneumonia

Procalcitonin in Pneumonia 3 patients with pneumonia on day 5 of antibiotics have a procalcitonin level drawn. PCT = 0.6 mcg/mL PCT = 0.1 mcg/mL PCT = 3.6 mcg/mL (was initially 7.2 mcg/mL) Who can most likely STOP antibiotics based on procalcitonin? How did others respond? Reveal the answer Best Answer Patient 2 👩🏻‍🦰 Explanation: …

Cefazolin vs Antistaphylococcal Penicillins

Cefazolin vs Antistaphylococcal Penicillins In which of the following patients would cefazolin be ADVANTAGEOUS over nafcillin for treatment of a MSSA infection? Patient 1 with CNS infection & recent C. difficile Patient 2 with osteomyelitis & hyperkalemia & LFTs How did others respond? Reveal the answer Best Answer Patient 2 🧔🏼 Explanation: Cefazolin is favorable …

Risk of C. difficile

Risk of C. difficile 3 patients are being discharged amoxicillin x 5 days cefdinir x 3 days levofloxacin x 10 days Whose antibiotic regimen is HIGHEST risk for C. difficile? How did others respond? Reveal the answer Best Answer 3️⃣ 👩🏻‍🦰 levofloxacin x 10 days Explanation: ALL antibiotics ⬆️ risk of C. difficile infection but …

Duplicate Anaerobic Activity

Duplicate Anaerobic Activity A is admitted to the with a new intra-abdominal fluid collection after a recent partial colectomy. Which empiric treatment needs the ADDITION of metronidazole for anaerobic coverage? A. CefepimeB. MeropenemC. Piperacillin/tazobactam How did others respond? Reveal the answer Best Answer Cefepime Explanation: IDSA cIAI guideline states cefepime is the only option here …

Treatment of CRE

Treatment of CRE A is seen in clinic with recurrent pyelonephritis. Her urine culture grows K. pneumoniae with this susceptibility: Meropenem = RTMP/SMX = SPIP/TAZ = I What is the BEST antibiotic choice based on available data? A. TMP/SMXB. CiprofloxacinC. Ceftazidime/AvibactamD. Cefiderocol How did others respond? Reveal the answer Best Answer TMP/SMX Explanation: Based on …