Patient Case: AmpC

Patient Case: AmpC A 38 year old  presents with suspected pyelonephritis and is started on empiric ceftriaxone. Hercultures grow Enterobacter cloacae with pending susceptibilities. What the best treatment? A) CeftriaxoneB) CefepimeC) Ceftazidime/Avibactam How did others respond? Reveal the answer Best Answer Cefepime AmpC beta-lactamase enzymes will hydrolyze most penicillins and many cephalosporins. These enzymes are often …

Patient Case: Confusion with Antibiotics

KASIC Patient Case: Confusion with Antibiotics An 80 year old man 👴 is diagnosed with cystitis and given an antibiotic 💊. After 3 days he begins complaining of muscle aches and after 4 days is experiencing new confusion. What antibiotic was he most likely prescribed? A) Amoxicillin-clavulanate B) CiprofloxacinC) Nitrofurantoin  How did others respond? Reveal the …

Patient Case: Staphylococcus aureus in a Urine Culture

KASIC Patient Case: Staphylococcus aureus in a Urine Culture A 55 year old 👱🏼‍♂️ is admitted for afib and put on a diltiazem drip. A urine culture collected in the ED shows >100K S. aureus. Patient is non-septic with no GU symptoms. What testing/treatment is best? A) Start vancomycin B) Recollect urine culturesC) Draw blood culturesD) Ignore  …

Patient Case: Cholecystitis Length of Therapy

KASIC Patient Case: Cholecystitis Length of Therapy A 39 year old is hospitalized with acute cholecystitis and treated with ceftriaxone. It’s POD1 laparoscopic cholecystectomy (no perforations). Her WBC is 15 and vitals are WNL. How long should she be treated with antibiotics?  A) Stop nowB) POD4C) POD7D) Until WBC is normal  How did others respond? Reveal …

Patient Case: Candida spp in Respiratory Culture

KASIC Patient Case: Candida spp in Respiratory Culture A 57 year old 👨🏻‍🦲 with a history of alcohol-related cirrhosis presents with confusion 😵‍💫. He is intubated on hospital day 3 and now has Candida spp growing from a sputum culture 🧫 What is the best therapy? How did others respond? Reveal the answer Best Answer …

Patient Cases: Role of repeat imaging in CAP

Patient Case: Role of Repeat Imaging in CAP A 75 year old 👵🏿 is hospitalized with radiographically confirmed community acquired pneumonia. She initially required oxygen support but has been treated with 5 days of antibiotics and is ready for discharge 🏡 Should a repeat chest X-ray be ordered to determine if she needs more antibiotics? …

Patient Case: ESBL E. coli

KASIC Patient Case: ESBL E. coli A 44 year old 👩🏽 with CKD and estimated CrCl 25 mL/min presents with 🔥urination without flank pain. Urine culture grows ESBL E. coli. Which treatment option is best? 🤔 A) Hold antibioticsB) Nitrofurantoin C) TMP/SMXD) Meropenem  How did others respond? Reveal the answer Best Answer TMP/SMX. 2022 IDSA Guidelines …

Patient Case: Cystitis with history of C.difficile

Patient Case: Cystitis with History of c.difficile A 25 year old  presents to clinic with frequent urination and is diagnosed with cystitis. She has a history of C. difficile. Which option is lowest risk for C. difficile recurrence? A) Cefdinir B) CiprofloxacinC) Nitrofurantoin  How did others respond? Reveal the answer Best Answer Nitrofurantoin causes minimal damage to the GI flora …