COVID-19 Management

is admitted with COVID-19. His symptoms began 2 weeks ago. He is on high flow oxygen but NOT immunocompromised.

What is the best treatment option?

A. Baricitinib + steroid
B. Remdesivir
C. Remdesivir + steroid
D. Azithromycin

How did others respond?

Reveal the answer

Best Answer:

Baricitinib + steroid

Explanation: The archived NIH COVID-19 guidelines make recommendations based on oxygen requirements, risk factors for severe disease and bleeding risk 🩸

Our patient is on high flow O2, so he should get dexamethasone + baricitinib. Remdesivir is unlikely to help >10 days after symptom onset.

Empiric antibiotics are NOT recommended ❌ Appropriate immunomodulatory therapy is associated with ⬇️ secondary bacterial infections.

Stabilizing and discharging patients quickly helps support antimicrobial stewardship 🎉