Carbapenems in Beta-Lactam Allergies

Carbapenems in Beta-Lactam Allergies is admitted to the with ESBL E. coli pyelonephritis. They have allergies (difficulty breathing) to TMP/SMX, ciprofloxacin, and ceftriaxone. Meropenem is ordered. Is this SAFE to give? How did others respond? Reveal the answer Best Answer: Yes Explanation: 2022 AAAAI/ACAAI Drug Allergy Practice Parameter states in patients WITHOUT severe delayed hypersensitivity …

Penicillin Allergy History

Penicillin Allergy History Two patients are admitted with neurosyphilis and penicillin allergies. 1: father was penicillin allergic, has not taken 2: difficulty breathing after 1st dose of amoxicillin Which patient(s) likely require DESENSITIZATION to penicillin? How did others respond? Reveal the answer Best Answer: Patient 2 πŸ‘±πŸΌβ€β™€οΈ Explanation: Patient 2 πŸ‘±πŸΌβ€β™€οΈ has a previous SEVERE …

Salmonella Management

Salmonella Management A 30 year old with no past medical/travel history presents to clinic for 2 days of diarrhea. She has not changed her diet but has been eating raw vegetables A stool sample is positive for Salmonella spp. What is the MOST APPROPRIATE option? A. Rehydration onlyB. CeftriaxoneC. CiprofloxacinD. Salmonella vaccine How did others …

TMP/SMX for Cellulitis

TMP/SMX for Cellulitis undergoes I&D in the emergency room and is sent home with TMP/SMX Wound culture grows MRSA & Streptococcus pyogenes Do antibiotics need to be changed? How did others respond? Reveal the answer Best Answer: No Explanation: TMP/SMX is active against MRSA and beta-hemolytic Streptococcus spp. Historically, it was thought TMP/SMX was INACTIVE …

Aerococcus Infection

Aerococcus Infection has dysuria & a urine culture growing Aerococcus urinae Which antibiotic is MOST LIKELY to be active against this isolate? A. CiprofloxacinB. PenicillinC. TMP/SMX How did others respond? Reveal the answer Best Answer: Penicillin Explanation: Various Aerococcus spp. can have different resistance patterns. Resistance in A. urinae is common with both ciprofloxacin and …

C. difficile Colonization

C. difficile Colonization 2 patients have a C. difficile PCR test and toxin EIA. 1: has cirrhosis, takes lactulose, normal WBC, no changes in diarrhea 2: febrile, took ciprofloxacin last week, having diarrhea Which patient(s) should be treated for C. difficile? How did others respond? Reveal the answer Best Answer: Patient 2 πŸ‘¨πŸ»β€πŸ¦° Explanation: This …

Leukocytosis

Leukocytosis is admitted to the with lupus nephritis. She is started on therapy including a corticosteroid The next day, leukocytosis is noted. What is the MOST LIKELY explanation? A. New infectionB. Medication side effectC. MalignancyD. Lab error How did others respond? Reveal the answer Best Answer: Medication side effect Explanation: When corticosteroids are started, they …

Non-Purulent Cellulitis

Non-Purulent Cellulitis is admitted to the for cellulitis. NO purulence is noted on exam and she has no relevant past medical history Which antibiotic is NOT recommended per IDSA guidelines for non-purulent cellulitis? A. CefazolinB. DicloxacillinC. NafcillinD. Vancomycin How did others respond? Reveal the answer Best Answer: Vancomycin Explanation: IDSA skin/soft tissue guidelines state that …

Biofilms

Biofilms is on chronic TPN and admitted to the with a MRSA bloodstream infection related to her IV line. After 4 days of vancomycin therapy, her blood culture is still positive. What is the MOST LIKELY reason? A. Biofilm on IV lineB. Vancomycin resistanceC. TPN inhibits vancomycin How did others respond? Reveal the answer Best …