Why Prolong a Beta-Lactam Infusion? Prolonged infusions of beta-lactam antibiotics increase time above MIC. Which patient would MOST likely benefit from a prolonged infusion? 1. Poor renal function 2. Critically-ill + MIC 3. Clinically stable + low MIC How did others respond? Reveal the answer Best Answer: Patient 2 👱🏼♀️ Explanation: Prolonged infusions of beta-lactams …
Ceftriaxone at Day 3 for Cystitis is admitted to the and found to have cystitis but no flank pain. HCG is negative. She is started on ceftriaxone At day 3, vitals are stable and symptoms have resolved. Her urine culture grew pan-susceptible E. coli What is the BEST antibiotic plan? A. DiscontinueB. De-escalateC. Escalate How …
Bilateral Lower Extremity Cellulitis A with CHF presents with shortness of breath & redness/swelling of both legs. He is afebrile & WBC is normal. Does he need antibiotics for bilateral lower extremity cellulitis? A. Yes IV antibiotics 💉B. Yes PO antibiotics 💊C. No antibiotics 🚫 How did others respond? Reveal the answer Best Answer: No …
Beta-Lactam Selection in Community-Acquired Pneumonia A medical student is presenting on a patient with community-acquired pneumonia. The team agrees they want to treat with a beta-lactam + macrolide. Which beta-lactam recommended per the 2019 ATS/IDSA guidelines is LOWEST risk for Clostridioides difficile? A. Ampicillin/sulbactamB. CefotaximeC. CeftriaxoneD. Ceftaroline How did others respond? Reveal the answer Best …
Antibiotic Duration in Intra-Abdominal Infections is admitted to the for cholecystitis & had a percutaneous drain placed yesterday. Her drain will be removed before discharge tomorrow. When should antibiotics be stopped? A. Post-op day 4B. Day 7C. Day 10D. Day 14 How did others respond? Reveal the answer Best Answer: Post-op Day 4 2024 Surgical …
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Anaerobe Awareness in Intra-Abdominal Infections is admitted to the with perforated diverticulitis & a blood culture growing PAN-SUSCEPTIBLE E. coli What is the MOST appropriate antibiotic regimen? A. AmpicillinB. Ampicillin/sulbactamC. Ceftriaxone How did others respond? Reveal the answer Best Answer Ampicillin/sulbactam Explanation: Surgical Infection Society guidelines recommend anti-anaerobic activity in intra-abdominal infections, even when de-escalating. …
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The Pneumonia Formerly Known as HCAP is admitted to the for NON-SEVERE pneumonia. She lives in a nursing home but has not been hospitalized or received antibiotics within the last 2 years. What organism(s) should her antibiotic regimen EMPIRICALLY cover? A. S. pneumoniaeB. MRSAC. P. aeruginosaD. All of the above How did others respond? …
Cascade Reporting A is growing Pseudomonas aeruginosa with this susceptibility: Cefepime = S Piperacillin/tazobactam = S Meropenem = S Ciprofloxacin = R Is IMIPENEM susceptible? A. Yes B. No C. Maybe? Call lab How did others respond? Reveal the answer Best Answer Maybe? Call lab 📞 Explanation: Many labs use cascade reporting, where not …
Stenotrophomonas maltophilia Respiratory Culture has a chronic tracheostomy with a sputum culture growing Stenotrophomonas maltophilia. He is afebrile, has no change in secretions & doesn’t have consolidations on chest X-ray. Does he need treatment? How did others respond? Reveal the answer Best Answer: No, don’t treat 🛑 Explanation: Stenotrophomonas maltophilia is a nosocomial organism BUT …
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Antibiotic Selection in Pancreatitis presents to the with abdominal pain and infected pancreatic necrosis. Which empiric antibiotic regimen has appropriate coverage AND good pancreatic tissue penetration? How did others respond? Reveal the answer Best Answer: Piperacillin/tazobactam Explanation: Empiric regimens should target enteric gram-negatives and anaerobes. Not all antibiotics have proven efficacy or are known to …