Cerebrospinal Fluid Analysis

Cerebrospinal Fluid Analysis A is started on empiric antibiotics for suspected bacterial meningitis. A lumbar puncture is performed and cerebrospinal fluid (CSF) analysis reveals 0 WBC, protein 45 mg/dL, and a CSF/plasma glucose ratio of 0.6. Additionally, no organisms are seen on Gram stain and a CSF PCR is negative. Antibiotics are de-escalated. Is this …

Imipenem-Resistant Morganella

Imipenem-Resistant Morganella is diagnosed with a hepatic abscess. Blood cultures reveal Morganella morganii resistant to imipenem but susceptible to ertapenem. Can ertapenem be used for outpatient parenteral antibiotic therapy? How did others respond? Reveal the answer Best Answer: Yes Explanation: Proteus, Morganella, and Providencia spp. are inherently less susceptible to imipenem through non-carbapenemase mechanisms. Cross-resistance …

Shiga Toxin-Producing E. coli

Shiga Toxin-Producing E. coli An otherwise healthy presents to the ED for dehydration from frequent . A GI panel is sent and the patient is discharged after receiving IV fluids. The GI panel returns positive with Shiga toxin-producing E. coli. What antibiotics should be prescribed? A. CiprofloxacinB. AzithromycinC. No antibiotics How did others respond? Reveal …

Carbapenems in Beta-Lactam Allergies

Carbapenems in Beta-Lactam Allergies is admitted to the with ESBL E. coli pyelonephritis. They have allergies (difficulty breathing) to TMP/SMX, ciprofloxacin, and ceftriaxone. Meropenem is ordered. Is this SAFE to give? How did others respond? Reveal the answer Best Answer: Yes Explanation: 2022 AAAAI/ACAAI Drug Allergy Practice Parameter states in patients WITHOUT severe delayed hypersensitivity …

Penicillin Allergy History

Penicillin Allergy History Two patients are admitted with neurosyphilis and penicillin allergies. 1: father was penicillin allergic, has not taken 2: difficulty breathing after 1st dose of amoxicillin Which patient(s) likely require DESENSITIZATION to penicillin? How did others respond? Reveal the answer Best Answer: Patient 2 πŸ‘±πŸΌβ€β™€οΈ Explanation: Patient 2 πŸ‘±πŸΌβ€β™€οΈ has a previous SEVERE …

Salmonella Management

Salmonella Management A 30 year old with no past medical/travel history presents to clinic for 2 days of diarrhea. She has not changed her diet but has been eating raw vegetables A stool sample is positive for Salmonella spp. What is the MOST APPROPRIATE option? A. Rehydration onlyB. CeftriaxoneC. CiprofloxacinD. Salmonella vaccine How did others …

TMP/SMX for Cellulitis

TMP/SMX for Cellulitis undergoes I&D in the emergency room and is sent home with TMP/SMX Wound culture grows MRSA & Streptococcus pyogenes Do antibiotics need to be changed? How did others respond? Reveal the answer Best Answer: No Explanation: TMP/SMX is active against MRSA and beta-hemolytic Streptococcus spp. Historically, it was thought TMP/SMX was INACTIVE …

Aerococcus Infection

Aerococcus Infection has dysuria & a urine culture growing Aerococcus urinae Which antibiotic is MOST LIKELY to be active against this isolate? A. CiprofloxacinB. PenicillinC. TMP/SMX How did others respond? Reveal the answer Best Answer: Penicillin Explanation: Various Aerococcus spp. can have different resistance patterns. Resistance in A. urinae is common with both ciprofloxacin and …

C. difficile Colonization

C. difficile Colonization 2 patients have a C. difficile PCR test and toxin EIA. 1: has cirrhosis, takes lactulose, normal WBC, no changes in diarrhea 2: febrile, took ciprofloxacin last week, having diarrhea Which patient(s) should be treated for C. difficile? How did others respond? Reveal the answer Best Answer: Patient 2 πŸ‘¨πŸ»β€πŸ¦° Explanation: This …