Chelation with Fluoroquinolones and Tetracyclines - KASIC

Chelation with Fluoroquinolones and Tetracyclines

is started on oral ciprofloxacin for a UTI. They have a history of iron deficient anemia. Can they take cipro and iron supplements at the same time?

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Best Answer

No

Explanation: Fluoroquinolone and tetracycline serum concentrations are reduced when co-administered with polyvalent cation containing medication such as antacids and vitamins. This may increase risk for clinical failure and emergence of drug-resistant bacteria. If unable to use alternative antibiotics, administration of polyvalent cation containing medications should be separated from oral fluoroquinolone and tetracycline administration by several hours.

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