Non-AmpC Citrobacter spp

Non-AmpC Citrobacter spp   is admitted with pyelonephritis. Blood cultures grow a GNB that is identified as a Citrobacter spp by rapid diagnostics and cefepime is selected for treatment. Two days later, final identification and susceptibilities reveal a C. koseri susceptible to cefazolin. Can antibiotics be deescalated to cefazolin?   How did others respond? Reveal …

Non-faecium VRE

Non-faecium VRE   has a diabetic foot osteomyelitis . Blood cultures grow vancomycin-resistant Enterococcus gallinarum which is susceptible to ampicillin. The patient is on empiric vancomycin and piperacillin-tazobactam . Should vancomycin be changed to daptomycin for this VRE? How did others respond? Reveal the answer Best Answer No Explanation: Enterococcus gallinarum is intrinsically resistant to …

Penicillins for MSSA

Penicillins for MSSA has pneumonia . A sputum culture grows methicillin-susceptible S. aureus susceptible to oxacillin, amoxicillin-clavulanate, and cefazolin. Oral amoxicillin is initially ordered. Is this appropriate? A. YesB. No How did others respond? Reveal the answer Best Answer No Explanation: MSSA commonly makes a penicillinase and should be considered resistant to penicillin, amoxicillin, and …

Cephalosporins for VGS

Cephalosporins for VGS is admitted with a dental abscess. Blood cultures grow Viridans Group Streptococcus (VGS) that is susceptible to penicillin. Is cephalexin and metronidazole a good oral stepdown option to complete therapy? YesNo How did others respond? Reveal the answer Best Answer No Explanation: Cephalexin has unreliable activity against VGS. Penicillin activity against VGS …