Antibiotics in Pancreatitis

Antibiotics in Pancreatitis presents to the with severe abdominal pain & WBCs. A CT scan shows acute pancreatitis without gas, abscess, or necrosis. Do they need antibiotics? How did others respond? Reveal the answer Best Answer No 🚫 Explanation: Antibiotics are NOT typically indicated in acute pancreatitis. Most cases are due to common noninfectious causes …

Altered Mental Status and Bacteriuria

Altered Mental Status and Bacteriuria presents with confusion . A urinalysis finds bacteria . Does she need antibiotics? Yes No Need more information How did others respond? Reveal the answer Best Answer Need more information Explanation: 2019 IDSA guidelines on asymptomatic bacteriuria (ASB) recommend to OBSERVE elderly patients OFF antibiotics if they do not have …

Duration of Therapy in Necrotizing Fasciitis

Duration of Therapy in Necrotizing Fasciitis presented with necrotizing fasciitis from Streptococcus pyogenes. After 3 debridements, no further surgery is planned. He is afebrile x 48 hours after his last surgery and improving He is on penicillin + clindamycin. What is the BEST antibiotic plan? A. No changeB. Stop clindamycin C. Stop penicillin D. Stop …

Group A Strep Necrotizing Fasciitis

Group A Strep Necrotizing Fasciitis presents with necrotizing fasciitis. cultures grow Streptococcus pyogenes (Group A Streptococcus). The team orders penicillin + clindamycin. Your student asks why clindamycin is added since penicillin covers GAS. You tell them… Anti-toxin effect C. difficile risk Penicillin resistance No reason How did others respond? Reveal the answer Best Answer Anti-toxin …

De-escalation

De-Escalation develops hospital-acquired pneumonia & started on empiric vancomycin + cefepime. Sputum cultures grow E. coli with the following susceptibilities: Ceftriaxone = S Cefepime = S Piperacillin/tazobactam = S How did others respond? Reveal the answer Best Answer: Ceftriaxone Explanation: Ceftriaxone will cover the E. coli 🦠 but does not unnecessarily cover Pseudomonas aeruginosa 🚫 …

Linezolid or Vancomycin for MRSA Pneumonia

Linezolid or Vancomycin for MRSA Pneumonia A was recently in the for influenza.   He is readmitted 2 weeks later with pneumonia. Which EMPIRIC anti-MRSA agent is the best choice?1. Vancomycin2. Linezolid How did others respond? Reveal the answer Best Answer Vancomycin Explanation: Using empiric vancomycin can help preserve linezolid activity against vancomycin-resistant Enterococcus. Positioning …

Cefazolin vs Antistaphylococcal Penicillins

Cefazolin vs Antistaphylococcal Penicillins In which of the following patients would cefazolin be ADVANTAGEOUS over nafcillin for treatment of a MSSA infection? Patient 1 with CNS infection & recent C. difficile Patient 2 with osteomyelitis & hyperkalemia & LFTs How did others respond? Reveal the answer Best Answer Patient 2 🧔🏼 Explanation: Cefazolin is favorable …

Risk of C. difficile

Risk of C. difficile 3 patients are being discharged amoxicillin x 5 days cefdinir x 3 days levofloxacin x 10 days Whose antibiotic regimen is HIGHEST risk for C. difficile? How did others respond? Reveal the answer Best Answer 3️⃣ 👩🏻‍🦰 levofloxacin x 10 days Explanation: ALL antibiotics ⬆️ risk of C. difficile infection but …

Duplicate Anaerobic Activity

Duplicate Anaerobic Activity A is admitted to the with a new intra-abdominal fluid collection after a recent partial colectomy. Which empiric treatment needs the ADDITION of metronidazole for anaerobic coverage? A. CefepimeB. MeropenemC. Piperacillin/tazobactam How did others respond? Reveal the answer Best Answer Cefepime Explanation: IDSA cIAI guideline states cefepime is the only option here …

Treatment of CRE

Treatment of CRE A is seen in clinic with recurrent pyelonephritis. Her urine culture grows K. pneumoniae with this susceptibility: Meropenem = RTMP/SMX = SPIP/TAZ = I What is the BEST antibiotic choice based on available data? A. TMP/SMXB. CiprofloxacinC. Ceftazidime/AvibactamD. Cefiderocol How did others respond? Reveal the answer Best Answer TMP/SMX Explanation: Based on …