Empiric Antifungals in the ICUby Matthew Songin Patient Caseson Posted on presents with perforated diverticulitis and is started on empiric antibiotics and taken to surgery. After surgery, she is hemodynamically stable and in the ICU. Should empiric micafungin be added? How did others respond? Reveal the answer Best Answer No Explanation: In the ICU, empiric antifungal therapy should be reserved for patients with substantial risk factors and clinical instability (e.g. septic shock). In more stable patients, hold empiric antifungals and start treatment after a diagnosis is made (e.g. positive cultures for Candida spp.). Click here for details/references