Antimicrobials for Acute Bacterial Prostatitis

by Matthew Songin Patient Caseson Posted on

A 65-year-old man has suspected acute bacterial prostatitis. Local E. coli resistance rates to quinolones and TMP-SMX are ~30%. Can empiric ceftriaxone be used?

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Best Answer

Yes

Explanation: While quinolones and TMP-SMX are generally preferred for acute bacterial prostatitis, antimicrobial resistance may preclude use of these agents empirically. Alternative options that have been recommended include intravenous beta-lactam like ceftriaxone, ceftazidime, cefepime, piperacillin-tazobactam, and carbapenems.

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