How Long for Legionella?

A patient has finished 3 days of azithromycin 500 mg daily and has a positive Legionella urinary antigen. They are clinically stable. Should azithromycin be continued?

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Best Answer

No

Explanation: Legionella is a common causative pathogen of community-acquired pneumonia (CAP) that is covered by recommended empiric antibiotics. CAP duration is recommended to be a minimum of 3-5 days depending on clinical stability. Specific data on proven Legionella pneumonia is limited but has shown azithromycin 1.5 g administered over 3 or 5 days to be effective. Severe Legionella pneumonia may require longer durations guided by clinical stability.

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