Ceftazidime Spectrum of Activity

A 55-year oldis admitted to the with a productive cough and fever and started on empiric ceftazidime. Ceftazidime provides reliable coverage against ALL of the following bacteria EXCEPT…?

A. MSSA
B. Klebsiella spp
C. Pseudomonas aeruginosa
D. E. coli

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Best Answer

MSSA

Explanation: Ceftazidime has NO activity ❌ against MRSA and elevated MICs have been observed for MSSA making it less likely to be active relative to other cephalosporins like cefazolin. Ceftazidime also has relatively poor activity against Steptococci. 🦠